Name | Natamycin |
Classes |
Antiinfective Agent Dermatological/Topical Agent Topical Antiinfective Agent Ophthalmic Preparation |
Diseases |
Conjunctivitis Infectious Disease Keratitis |
Natamycin
Natamycin is a polyene amphoteric macrolide antibiotic that is effective against topical fungal infections.
Natamycin is indicated for the following fungal infections-
- Blepharitis
- Keratitis
- Conjunctivitis
Fungal keratitis
Adult: As 5% ophthalmic susp: Instill 1 drop into the conjunctival sac of the affected eye(s) 1-2 hourly, reduce to 1 drop 6-8 times daily after 3-4 days. Duration of treatment: 2-3 weeks. Gradually reduce dose at 4-7 day intervals.
Fungal blepharitis, Fungal conjunctivitis
Adult: As 5% ophthalmic susp: Instill 1 drop into the conjunctival sac of the affected eye(s) 4-6 times daily.
How to administer ophthalmic drops:
Common side effects caused by natamycin are as follows-
- Chest pain.
- Changes in vision
- eye irritation
- oedema
- excessive tearing
- rash
Special Precautions should be taken for patients with epithelial ulceration & Pregnancy and lactation.
Contraindication
Contraindicated in patients hypersensitive natamycin or other amphoteric macrolides, such as-