Name Natamycin
Classes Antiinfective Agent
Dermatological/Topical Agent
Topical Antiinfective Agent
Ophthalmic Preparation
Diseases Conjunctivitis
Infectious Disease
Keratitis

Natamycin

Natamycin is a polyene amphoteric macrolide antibiotic that is effective against topical fungal infections.

 

Natamycin is indicated for the following fungal infections-

  • Blepharitis
  • Keratitis
  • Conjunctivitis

Fungal keratitis

Adult: As 5% ophthalmic susp: Instill 1 drop into the conjunctival sac of the affected eye(s) 1-2 hourly, reduce to 1 drop 6-8 times daily after 3-4 days. Duration of treatment: 2-3 weeks. Gradually reduce dose at 4-7 day intervals.
 
Fungal blepharitis, Fungal conjunctivitis
Adult: As 5% ophthalmic susp: Instill 1 drop into the conjunctival sac of the affected eye(s) 4-6 times daily.
 
How to administer ophthalmic drops:

Common side effects caused by natamycin are as follows-

  • Chest pain.
  • Changes in vision
  • eye irritation
  • oedema
  • excessive tearing  
  • rash
Special Precautions should be taken for patients with epithelial ulceration & Pregnancy and lactation.

Contraindication

Contraindicated in patients hypersensitive natamycin or other amphoteric macrolides, such as-