Name | Sulfadimidine |
Classes |
Antiinfective Agent Antibiotic Macrolide |
Diseases |
Bronchitis Infectious Disease Otitis Pneumonia Shigellosis Sinusitis Tonsillitis UTI (Urinary Tract Infection) Wound |
Sulfadimidine
Sulfadimidine is a short acting antibacterial agent. These medicines are grouped under synthetic antimicrobial agents. These are commonly called sulfa drugs. It is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase.
It is indicated for treatment of
- Urinary tract infection
- Prostatitis
- Respiratory tract infection
- The recommended adult dose is 0.5 g to 1g taken three or four times daily.
- Sulfadimidine comes as a tablet or suspension to be taken by mouth with food to avoid gastric discomfort
- Antacids reduce the absorption of Sulfadimidine, therefore it should be taken 2 hours after sulfadimidine administration.
Side effects include-
- Stevens-Johnson's syndrome
- Diarrhea
- Nausea
- Vomiting
- Anemia in G6PD patients
- Crystalluria
- Pancreatitis
- Caution is needed for newborns as it induces jaundice by displacing bilirubin (bile pigment) from its binding protein
- Use with caution in individuals with liver/kidney diseases.
Contraindication
Contraindicated in patients hypersensitive to the medicine itself or other sulphonamides such as-
There's no known contraindications of the drug in terms of food and drinks.
Contraindicated in-
- Liver diseases
- Kidney diseases
- a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency
- Allergic to sulfa drugs