Name Sulfadimidine
Classes Antiinfective Agent
Antibiotic
Macrolide
Diseases Bronchitis
Infectious Disease
Otitis
Pneumonia
Shigellosis
Sinusitis
Tonsillitis
UTI (Urinary Tract Infection)
Wound

Sulfadimidine

Sulfadimidine is a short acting antibacterial agent. These medicines are grouped under synthetic antimicrobial agents. These are commonly called sulfa drugs. It is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase.

It is indicated for treatment of 

  • Urinary tract infection
  • Prostatitis
  • Respiratory tract infection
  • The recommended adult dose is 0.5 g to 1g taken three or four times daily.
  • Sulfadimidine comes as a tablet or suspension to be taken by mouth with food to avoid gastric discomfort
  • Antacids reduce the absorption of Sulfadimidine, therefore it should be taken 2 hours after sulfadimidine administration.

Side effects include-

  • Stevens-Johnson's syndrome
  • Diarrhea
  • Nausea
  • Vomiting
  • Anemia in G6PD patients
  • Crystalluria
  • Pancreatitis
  • Caution is needed for newborns as it induces jaundice by displacing bilirubin (bile pigment) from its binding protein
  • Use with caution in individuals with liver/kidney diseases.

Contraindication

Contraindicated in patients hypersensitive to the medicine itself or other sulphonamides such as-

There's no known contraindications of the drug in terms of food and drinks.

Contraindicated in-

  • Liver diseases
  • Kidney diseases
  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency
  • Allergic to sulfa drugs