Amlodipine + Valsartan is indicated for the treatment of essential hypertension. Amlodipine + Valsartan is used to treat adults with high blood pressure who aren't obtaining significant improvement on amlodipine or valsartan alone.

Hypertension (Hight Blood Pressure)

Amlodipine + Valsartan is available as tablets.

• Patients who cannot control their blood pressure with amlodipine 5 mg or valsartan 80 mg alone, may be administered Amlodipine + Valsartan 5 mg/80 mg.
• Patients who cannot manage their blood pressure with amlodipine 5 mg or valsartan 160 mg alone, may be given Amlodipine + Valsartan 5 mg/160 mg.
• Patients who cannot manage their blood pressure with amlodipine 10 mg or valsartan 160 mg alone, or with Amlodipine + Valsartan 5 mg/160 mg, may be given Amlodipine + Valsartan 10 mg/160 mg.
• Amlodipine + Valsartan should be used with caution in people who have hepatic impairment or biliary obstructive diseases. The maximum recommended dose of valsartan in patients with mild to severe hepatic impairment without cholestasis is 80 mg. 
• In patients with mild to severe hepatic impairment, no dosage recommendations for amlodipine have been provided.

Common side effects associated with Amlodipine + Valsartan are as follows-

• Nasopharyngitis
• Influenza
• Hypokalemia
• Headache
• Asthenia
• Oedema/Facial edema
• Flushing

Pharyngitis	Influenza	Headache
Asthenia	Edema	Flushing

• During the second and third trimesters of pregnancy, medications that act on the renin-angiotensin system impair fetal renal function and increase fetal and newborn morbidity and death.
• 0.4 percent of patients with simple hypertension treated with Valsartan + Amlodipine experienced excessive hypotension. Angiotensin receptor blockers may cause symptomatic hypotension in individuals with an active renin-angiotensin system, such as volume- and/or salt-depleted patients receiving high doses of diuretics.
• In patients with heart failure or a recent myocardial infarction, as well as those undergoing surgery or dialysis, start therapy carefully.